BEGIN:VCALENDAR VERSION:2.0 PRODID:-//swoogo.com//NONSGML kigkonsult.se iCalcreator 2.41.90// CALSCALE:GREGORIAN UID:34363661-6337-4664-b164-663466616162 BEGIN:VEVENT UID:e965a4e3a14cbb35404a416d9f272b4b7fb70602@swoogo.com DTSTAMP:20260915T225618Z DESCRIPTION:Canine mast cell tumors (MCTs) exhibit diverse biological behav ior\, ranging from lesions cured with surgical excision alone to highly ag gressive neoplasms associated with metastasis and cancer-related mortality . Historically\, assessment of clinically aggressive behavior relied on hi stologic appearance and clinical staging. Advances in pathology\, molecula r diagnostics\, and understanding of tumor biology have reshaped our under standing of disease behavior. This session will explore the evolution of r isk assessment in canine MCTs\, from traditional morphologic grading syste ms to recent approaches that incorporate proliferation indices\, KIT expre ssion patterns\, c-kit mutational analysis\, and lymph node evaluation. At tendees will also examine emerging concepts involving the tumor microenvir onment\, tumor heterogeneity\, genomic profiling and liquid biopsy-based t esting for detection of tumor-associated biomarkers. Through review of key studies and recent literature\, participants will gain a practical unders tanding for integrating diagnostic information to improve prediction of tu mor aggressiveness\, guide therapeutic decisions\, and communicate prognos tic assessment in dogs with mast cell neoplasia. DTSTART:20261014T180000Z DTEND:20261014T193000Z LAST-MODIFIED:20260915T225618Z LOCATION:https://idexx.swoogo.com/101426GeorgeWhatMakesanMastCellTumorAggre ssiveEvolutionofRiskAssessment/v/e SEQUENCE:0 STATUS:CONFIRMED SUMMARY:10.14.26 Specialist Webinar George What Makes an Mast Cell Tumor Ag gressive? Evolution of Risk Assessment from Microscope to Molecule TRANSP:OPAQUE X-ALT-DESC;FMTTYPE=text/html:

Canine mast cell tumors (MCTs) exhibit dive rse biological behavior\, ranging from lesions cured with surgical excisio n alone to highly aggressive neoplasms associated with metastasis and canc er-related mortality. Historically\, assessment of clinically aggressive b ehavior relied on histologic appearance and clinical staging. Advances in pathology\, molecular diagnostics\, and understanding of tumor biology hav e reshaped our understanding of disease behavior. This session will explor e the evolution of risk assessment in canine MCTs\, from traditional morph ologic grading systems to recent approaches that incorporate proliferation indices\, KIT expression patterns\, c-kit mutational analysis\, and lymph node evaluation. Attendees will also examine emerging concepts involving the tumor microenvironment\, tumor heterogeneity\, genomic profiling and l iquid biopsy-based testing for detection of tumor-associated biomarkers. T hrough review of key studies and recent literature\, participants will gai n a practical understanding for integrating diagnostic information to impr ove prediction of tumor aggressiveness\, guide therapeutic decisions\, and communicate prognostic assessment in dogs with mast cell neoplasia.

BEGIN:VALARM UID:62343165-6165-4666-b765-663539633334 ACTION:DISPLAY DESCRIPTION:Canine mast cell tumors (MCTs) exhibit diverse biological behav ior\, ranging from lesions cured with surgical excision alone to highly ag gressive neoplasms associated with metastasis and cancer-related mortality . Historically\, assessment of clinically aggressive behavior relied on hi stologic appearance and clinical staging. Advances in pathology\, molecula r diagnostics\, and understanding of tumor biology have reshaped our under standing of disease behavior. This session will explore the evolution of r isk assessment in canine MCTs\, from traditional morphologic grading syste ms to recent approaches that incorporate proliferation indices\, KIT expre ssion patterns\, c-kit mutational analysis\, and lymph node evaluation. At tendees will also examine emerging concepts involving the tumor microenvir onment\, tumor heterogeneity\, genomic profiling and liquid biopsy-based t esting for detection of tumor-associated biomarkers. Through review of key studies and recent literature\, participants will gain a practical unders tanding for integrating diagnostic information to improve prediction of tu mor aggressiveness\, guide therapeutic decisions\, and communicate prognos tic assessment in dogs with mast cell neoplasia. TRIGGER:-PT15M END:VALARM END:VEVENT END:VCALENDAR